Επαγγελματικη Προυπηρεσια
10.2019 - σήμερα: Διευθυντής Νευροχειρουργικής Νοσοκομείου Metropolitan
01.2010 - 10.2019: Αρχίατρος (Oberarzt) Πανεπιστημιακής Νευροχειρουργικής Κλινικής Κολωνίας, Γερμανία
11.2008 - 04.2009: Εκπαίδευση στην Παιδο-νευροχειρουργική, Μόναχο, Γερμανία
12.2005 - 08.2010: Ειδικότητα Νευροχειρουργικής, Α΄ Νευροχειρουργική Κλινική, Πανεπιστημιακό Νοσοκομείο ΑΧΕΠΑ, Θεσσαλονίκη
04.2005 - 09.2005: Επιστημονικός συνεργάτης Νευροχειρουργικής Κλινικής, Τζάνειο Νοσοκομείο, Αθήνα
09.2003 - 12.2004: Ειδικότητα Γεν. Χειρουργικής, ΝΙΜΤΣ, Αθήνα
01.2002 - 04.2003: Υπηρεσία υπαίθρου, ΚΥ Μακρυχωρίου, Καρδίτσα
Ακαδημαϊκοί Τίτλοι
- Επ. Καθηγητής (Pr.-Doz.) Πανεπιστημίου της Κολωνίας (2019).
- Διδάκτωρ (PhD) Ιατρικής Σχολής του Αριστοτελείου Πανεπιστημίου Θεσσαλονίκης (2011)
Διδακτορική Διατριβή: “Μελέτη της έκφρασης ομάδας γονιδίων και ενζύμων που εμπλέκονται στο μεταβολισμό φαρμάκων και ξενοβιοτικών ουσιών σε όγκους εγκεφάλου”.
Εξειδίκευση
Νευρο-ογκολογία
- 2011 - 2019. Τακτικό μέλος νευρο-ογκολογικού συμβουλίου της πανεπιστημιακής κλινικής της Κολωνίας. Συνυπέυθυνος εξωτερικού ιατρείου νευρο-ογκολογίας.
- Συγγραφέας των κατευθυντήριων οδηγιών της ευρωπαϊκής νευρο-ογκολογικής εταιρίας (EANO Guidelines) για τα μηνιγγιώματα (Lancet Oncol, 2016) και ακουστικά νευρινώματα (Neuro-Oncol, 2019).
- Ερευνητής (SI/PI) σε πολυκεντρικές μελέτες στον τομέα της Νευρο-ογκολογίας (CeTeG, Glarius, MetMab, Stellar).
Χειρουργική Βάσεως Κρανίου
- Διοργανωτής (Director) του διεθνούς Εκπαιδευτικού Σεμιναρίου Χειρουργικής Βάσεως του Κρανίου στην Κολωνία (Cologne International Skull Base Course)
- Εκπαιδευτής (Invited Faculty) στο διεθνές Σεμινάριο νευροχειρουργικής ανατομίας, Αθήνα (White matter & Neurosurgical Anatomy Course, Athens)
- Εκπαιδευτής (Invited Faculty) στο διεθνές Σεμινάριο Χειρουργικής Βάσεως του Κρανίου, Erlangen (Erlangen Interdisciplinary Course for Endoscopic and Microscopic Surgery of the Skull Base)
Ελάχιστα Επεμβατική Χειρουργική Σπονδυλικής Στήλης
- Κάτοχος Διπλώματος Master της Γερμανικής Εταιρίας Σπονδυλικής Στήλης (DWG Master Zertifikat)
Βραβεία
- European Association of Neurosurgical Societies (ΕΑΝS) Research Prize – Honorable Mention (04.2018)
- 1ο Βραβείο Ερευνητικής Εργασίας, με τίτλο «Μελέτη της έκφρασης ομάδας γονιδίων και ενζύμων που εμπλέκονται στο μεταβολισμό χημειοθεραπευτικών φαρμάκων σε όγκους εγκεφάλου». 24ο Πανελλήνιο Νευροχειρουργικό συνέδριο, Κρήτη (05.2010)
- Βραβείο καλύτερης προφορικής ανακοίνωσης με τίτλο «Survival effects of a strategy favoring second-line multimodal treatment compared to supportive care in glioblastoma patients at first progression». 31ο Πανελλήνιο Νευροχειρουργικό συνέδριο, Ιωάννινα (06.2017)
- Απονομή Βραβείου για αριστεία στον κύκλο μαθημάτων παθολογικής ανατομικής (04.2000)
Μέλος Εταιριών
- Ελληνική εταιρία νευροχειρουργικής (ΕΝΧΕ)
- Γερμανική εταιρία νευροχειρουργικής (DGNC)
- Γερμανική εταιρία σπονδυλικής στήλης (DWG)
- Ευρωπαϊκή εταιρία νευροχειρουργικής (EANS)
- Ελληνο-Αμερικανική νευροχειρουργική εταιρία (GANS)
- Ευρωπαϊκή Νευρο-ογκολογική Εταιρία (ΕΑΝΟ)
Publications
- EANO Guideline on the Diagnosis and Treatment of Vestibular Schwannoma.
Goldbrunner R, Weller M, Regis J, Lund-Johansen M, Stavrinou P, Reuss D, Evans DG, Lefranc F, Sallabanda K, Falini A, Axon P, Sterkers O, Fariselli L, Wick W, Tonn JC. Neuro Oncol. 2019 Aug 28. - EANO Guidelines for the diagnosis and treatment of meningiomas. Goldbrunner R, Minniti G, Preusser M, Jenkinson MD, Sallabanda K, Houdart E, von Deimling A, Stavrinou P, Lefranc F, Lund-Johansen M, Moyal EC, Brandsma D, Henriksson R, Soffietti R, Weller M. Lancet Oncol. 2016 Sep;17(9):e383-91.
- Survival effects of a strategy favoring second-line multimodal treatment compared to supportive care in glioblastoma patients at first progression Stavrinou P, Kalyvas A, Grau S, Hamisch C, Galldiks N, Katsigiannis S, Kabbasch C, Timmer M, Goldbrunner R, Stranjalis G.. J Neurosurg. J Neurosurg. 2018 Nov 1:1-6.
- Impact of time to initiation of radiotherapy on survival after resection of newly diagnosed glioblastoma. Katsigiannis S, Krischek B, Barleanu S, Grau S, Galldiks N, Timmer M, Kabbasch C, Goldbrunner R, Stavrinou P. Radiat Oncol. 2019 Apr 29;14(1):73.
- Brain metastases from esophageal cancer: A retrospective analysis of the outcome after surgical resection followed by radiotherapy.
Stavrinou P, Plambeck L, Proescholdt M, Ghadimi M, Goldbrunner R, Grau S.
Medicine (Baltimore). 2019 Aug;98(34) - Perkuhn M, Stavrinou P, Thiele F, Shakirin G, Mohan M, Garmpis D, Kabbasch C, Borggrefe J. Clinical evaluation of a parametric deep learning model for glioblastoma segmentation using heterogeneous magnetic resonance imaging data from clinical routine. J Invest Radiol. 2018 Sep;13(2):144.
- Risk factors for chronic subdural hematoma recurrence identified using quantitative computed tomography analysis of hematoma volume and density. Stavrinou P, Katsigiannis S, Lee JH, Hamisch C, Krischek B, Mpotsaris A, Timmer M, Goldbrunner R.World Neurosurg. 2017 Mar;99:465-470
- Independent predictors for functional outcome after drainage of chronic subdural hematoma identified using a logistic regression model. Katsigiannis S, Hamisch C, Krischek B, Timmer M, Mpotsaris A, Goldbrunner R, Stavrinou P. J Neurosurg Sci. 2017 Jul.
- Navigated transtubular extraforaminal decompression of the L5 root at the lumbosacral junction : clinical data, radiographic features and outcome analysis. Stavrinou P, Härtl R, Krischek B, Kabbasch C, Mpotsaris A, Goldbrunner R. Biomed Res Int. 2016;2016:3487437
- Identifying risk factors and proposing a risk-profile scoring scale for perioperative complications in carotid endarterectomies. Neurosurg Sci. Stavrinou P, Bergmann J, Palkowiz S, Goldbrunner R, Rieger B. 2016 Mar;60(1):11-7.
- Expression profiles of genes related to drug metabolism in human brain tumors. Stavrinou P, Mavrogiorgou MC, Polyzoidis S, Kreft-Kerekes V, Timmer M, Marselos M, Pappas P. PLoS One. 2015 Nov 18;10(11)
- Children with tethered cord syndrome of different etiology benefit from microsurgery – a single institution experience. Stavrinou P, Kunz M, Lehner M, Heger A, Müller-Felber W, Tonn JC, Peraud A.Childs Nerv Syst. 2011 May;27(5):803-10.
- Volumetric evaluation of FET uptake and MRI contrast enhancement in newly diagnosed glioblastoma prior to treatment. Lohmann P, Stavrinou P, Lipke K, Bauer EK, Ceccon G, Werner JM, Fink GR, Shah NJ, Langen KL, Galldiks N.
Eur J Nucl Med Mol Imaging. Mar;46(3):591-602. - Primary extracerebral meningeal glioblastoma: clinical and pathological analysis. Stavrinou P, Magras I, Stavrinou LC, Zaraboukas T, Polyzoidis KS, Selviaridis P. Cent Eur Neurosurg. 2010 Feb;71(1):46-9.
- ACTB and SDHA are suitable endogenous reference genes for gene expression studies in human astrocytomas using quantitative RT-PCR. Röhn G, Koch A, Krischek B, Stavrinou P, Goldbrunner R, Timmer M. Technol Cancer Res Treat. Sept 2018
- Expression of CD40 Correlates Negatively with Overall and Progression-Free Survival of Low- and High-Grade Gliomas.Werner JM, Kuhl S, Ulrich K, Krischek B, Stavrinou P, Goldbrunner R, Timmer M. World Neurosurg. 2019 Oct;130:e17-e25.
- Death receptor 6 (DR6) is overexpressed in astrocytomas. Stegmann S, Werner JM, Kuhl S, Röhn G, Krischek B, Stavrinou P, Goldbrunner R, Timmer M. Anticancer Res. 2019 May;39(5):2299-2306.
- Heterogeneity of Human Gliomas: Glutathione-S-Transferase Expression Profile During Disease Progression and Under Systemic Therapy.Tjiong R, Stavrinou P, Röhn G, Krischek B, Koch A, Goldbrunner R, Timmer M. Anticancer Res. 2019 Apr;39(4):1795-1805.
- Qualitative and Quantitative Analysis of IDH1 Mutation in Progressive Gliomas by Allele-Specific qPCR and Western Blot Analysis.Perrech M, Dreher L, Röhn G, Stavrinou P, Krischek B, Toliat M, Goldbrunner R, Timmer M. Technol Cancer Res Treat. 2019 Jan 1;18
- Long-Term Outcome and Health-Related Quality of Life of Elderly Patients After Meningioma Surgery.Timmer M, Seibl-Leven M, Wittenstein K, Grau S, Stavrinou P, Röhn G, Krischek B, Goldbrunner R. World Neurosurg. 2019 May;125:e697-e710
- WEB embolization versus stent-assisted coiling: comparison of complication rates and angiographic outcomes. Kabbasch C, Goertz L, Siebert E, Herzberg M, Borggrefe J, Krischek B, Stavrinou P, Dorn F, Liebig T. J Neurointerv Surg. 2019 Aug;11(8):812-816.
- Impact of aneurysm shape and neck configuration on cerebral infarction during microsurgical clipping of intracranial aneurysms.Goertz L, Hamisch C, Kabbasch C, Borggrefe J, Hof M, Dempfle AK, Lenschow M, Stavrinou P, Timmer M, Brinker G, Goldbrunner R, Krischek B.J Neurosurg. 2019 Apr 12:1-9.
- Elective Treatment of Additional and Recurrent Aneurysms in Patients with a Previous Subarachnoid Hemorrhage: A Single-Center Analysis of Complications and Clinical Outcome.Goertz L, Brinker G, Hamisch C, Kabbasch C, Borggrefe J, Hof M, Timmer M, Stavrinou P, Goldbrunner R, Krischek B. World Neurosurg. 2019 May;125:e1196-e1202
- Independent Risk Factors for Postoperative Seizures in Chronic Subdural Hematoma Identified by Multiple Logistic Regression Analysis .Goertz L, Speier J, Schulte AP, Stavrinou P, Krischek B, Goldbrunner R, Timmer M. World Neurosurg. 2019 Aug 14. pii: S1878-8750(19)32184-9.
- Safety and efficacy of the Neuroform Atlas for stent-assisted coiling of intracranial aneurysms: A multicenter experience.Goertz L, Dorn F, Siebert E, Herzberg M, Borggrefe J, Schlamann M, Krischek B, Stavrinou P, Mpotsaris A, Bohner G, Liebig T, Kabbasch C.J Clin Neurosci. 2019 Oct;68:86-91.
- Application of Intraoperative FLOW 800 Indocyanine Green Videoangiography Color-Coded Maps for Microsurgical Clipping of Intracranial Aneurysms. Goertz L, Hof M, Timmer M, Schulte AP, Kabbasch C, Krischek B, Stavrinou P, Reiner M, Goldbrunner R, Brinker G. World Neurosurg. 2019 Jul 19. pii: S1878-8750(19)32019-4.
- Preoperative three-dimensional angiography reduces ischemic complications during clipping of ruptured intracranial aneurysms. Goertz L, Hamisch C, Telentschak S, Kabbasch C, Borggrefe J, von Spreckelsen N, Stavrinou P, Timmer M, Goldbrunner R, Brinker G, Krischek B. World Neurosurg. 2018 Dec;120:e1163-e1170.
- Impact of aneurysm shape on morbidity after clipping of unruptured intracranial aneurysms. Goertz L, Kasuya H, Hamisch C, Kabbasch C, Von Spreckelsen N, Ludyga D, Timmer M, Stavrinou P, Goldbrunner R, Krischek B. Acta Neurochirurg. 2018 Nov;160(11):2169-2176
- Impact of Aneurysm Shape on Intraoperative Rupture During Clipping of Ruptured Intracranial Aneurysms. Goertz L, Hamisch C, Telentschak S, Kabbasch C, von Spreckelsen N, Stavrinou P, Timmer M, Goldbrunner R, Brinker G, Krischek B. World Neurosurg. 2018 Oct;118:e806-e812
- Treatment of intracranial aneurysms with the pipeline embolization Device only: a single center experience. Maus V, Mpotsaris A, Borggrefe J, Abdullayev N, Liebig T, Dorn F, Stavrinou P, Chang DH, Kabbasch C. Neurointervention. 2018 Sep;13(2):144.
- The use of flow-diverter in ruptured, dissecting intracranial aneurysms of the posterior circulation. Maus V, Mpotsaris A, Dorn F, Möhlenbruch M, Borggrefe J, Stavrinou P, Abdullayev N, Barnikol UB, Liebig T, Kabbasch C. World Neurosurg. 2018 Mar;111.
- Expression of FAS-L differs from primary to relapsed low-grade gliomas and predicts progression-free survival. Werner JM, Kuhl S, Stavrinou P, Röhn G, Krischek B, Blau T, Goldbrunner R, Timmer M. Anticancer Res. 2017 Dec;37(12):6639-6648.
- Discordance and conversion rates of progesterone-, estrogen-, and HER2/neu-receptor status in primary breast cancer and brain metastasis mainly triggered by hormone therapy. Timmer M, Werner JM, Röhn G, Ortmann M, Blau T, Cramer C, Stavrinou P, Krischek B, Mallman P, Goldbrunner R.
Anticancer Res. 2017 Sep;37(9):4859-4865. - Pipeline embolization device for treatment of intracranial aneyrysms-the more the better? A single-center retrospective observational study. Kabbasch C, Mpotsaris A, Behme D, Dorn F, Stavrinou P, Liebig T.J Vasc Interv Neurol. 2016 Oct;9(2):14-20.
Serum levels of S-100B after recreational scuba diving. Stavrinou LC, Kalamatianos T, Stavrinou P, Papasilekas T, Psachoulia C, Tzavara C, Stranjalis G. Int J Sports Med. 2011 Dec;32(12):912-5. - Students do not consider all subjects to be equally relevant. Α method for quantifying relevance; implications for curriculum timetabling, teaching and learning, and student assessment of teachers. Tseretopoulou X, Stratou A, Stavrinou P, Souretis G, Dimoliatis I.D.K. Arch Hell Med. 2011 Mar;28(2):227-233.
Spinal synovial cysts: pathogenesis, diagnosis and surgical treatment in a series of seven cases and literature review. Boviatsis EJ, Stavrinou LC, Kouyialis AT, Gavra MM, Stavrinou P, Themistokleous M, Selviaridis P, Sakas DE. Eur Spine J. 2008 Jun;17(6):831-7. - Is clipping better than coiling in the treatment of patients with oculomotor nerve palsies induced by posterior communicating artery anerysms? A systematic review and meta-analysis. Zheng F, Dong Y, Xia P, Mpotsaris A, Stavrinou P, Brinker G, Goldbrunner R, Krischek B. Clin Neurol Neurosurg. 2017 Feb;153:20-26.
- Early or late cranioplasty following decompressive craniotomy for traumatic brain injury: a systematic review and meta-analysis. Zheng F, Xu H, von Spreckelsen N, Stavrinou P, Timmer M, Goldbrunner R, Cao F, Ran Q, Li G, Fan R, Zhang Q, Chen W, Yao S, Krischek B. J Int Med Res. 2018 Jan 1.
- Should preventive antibiotics be used in patients with acute stroke? A systematic review and meta-analysis. Zheng F, Spreckelsen NV, Zhang X, Stavrinou P, Timmer M, Dohmen C, Goldbrunner R, Cao F, Zhang Q, Ran Q, Li G, Fan R, Yao S, Krischek B.
PLoS One. 2017 Oct 19;12(10). - Intetdisciplinary treatment of intracranial infectious anerysms. Hamisch CA, Mpotsaris A, Timmer M, Reiner M, Stavrinou P, Brinker G, Goldbrunner R, Krischek B. Cerebrovasc Dis. 2016;42(5-6):493-505.
- Cervical epidural plasmacytoma presenting as ascenting paraparesis. Lourbopoulos A, Ioannidis P, Balogiannis I, Stavrinou P, Koletsa T, Karacostas D. Spine J. 2011 May;11(5).
- Primary osseous leiomyosarcoma of the spine: a rare entity-case report and review of the literature. Potsi M, Stavrinou P, Patsinakidis N, Hatzibougias D, Foroglou N, Karayanopoulou G, Kalogera-Founzila A. J Neurol Surg A Cent Eur Neurosurg. 2012 Aug;73(4):238-42.
- Extracranial vertebral artery aneurysm presenting as a chronic mass lession. Stavrinou LC, Stranjalis G, Stavrinou P, Bontozoglou N, Sakas DE. Case Rep Med. 2010;2010:938219.
- Trigeminocardiac reflex and ipsilateral mydriasis during stereotactic brain tumor biopsy. An insight into the anatomical and physiological pathways involved. Stavrinou P, Foroglou N, Patsalas I, Selviaridis P. Acta Neurochir (Wien). 2010 Apr;152(4):727-8.
- Subependymal giant cell astrocytoma with intratumoral hemorrhage in the absence of tuberous sclerosis Stavrinou P, Spiliotopoulos A, Patsalas I, Balogiannis I, Karkavelas G, Polyzoidis K, Selviaridis P.. J Clin Neurosci. 2008 Jun;15(6):704-6.
- Large intraparotid facial nerve schwannoma: case report and review of the literature Salemis NS, Karameris A, Gourgiotis S, Stavrinou P, Nazos K, Vlastarakos P, Tsiambas E, Tsohataridis E. Int J Oral Maxillofac Surg. 2008 Jul;37(7):679-81.
- Perforated appendix and periappendicular abscess within an inguinal hernia. Salemis NS, Nisotakis K, Nazos K, Stavrinou P, Tsohataridis E. Hernia. 2006 Dec;10(6):528-30.