PREVIOUS EXPERIENCE
- 09/2014-09/2015: Scientific Associate, Neurology Clinic, University Hospital of Patra
- 05/2014-currently: Private practice as a Neurology Associate, Olympion Private Clinic, Patra
- 10/2013-04/2014: Specialty training, Department of Neurosonology, Neurology Clinic, Geneva University Hospital, Switzerland (salaried position)
- 07/2013-10/2013: Postgraduate training, Department of Neurosonology, Neurology Clinic, Geneva University Hospital, Switzerland (salaried position)
- 10/2012-07/2013: Postgraduate training, Department of Vascular Brain Diseases, Neurology Clinic, Geneva University Hospital, Switzerland (salaried position)
- 07/2011-10/2011: Specialty training in Psychiatry, University of Patra
- 07/2007-04/2011: Specialty training in Neurology, University of Patra
- 03/2006-06/2007: Key research on glioblastomas (salaried post-doctoral associate) in the context of his doctoral dissertation at the University of Illinois, Peoria, USA
- 02/2005-02/2006: Military service - Hellenic Air Force Physician, Hellenic Air Force summer resort unit, Skotina, Pieria
- 07/2004-01/2005: Specialty training, Internal Medicine Clinic, General Hospital of Krestena
- 09/2001-01/2003: Rural service, Korinos, Pieria
EDUCATION
- 10/1995-06/2001: Ioannina University Medical School, Degree in Medicine, grade magna cum laude (7.96)
- 01/2003-09/2003: Key research on angiogenesis, Biochemistry Lab, Ioannina University Medical School
- 09/2003-07/2004: Key research on glioblastomas in the context of his doctoral dissertation, Neurosurgical Institute, Ioannina University Medical School
- 03/2006-06/2007: Key research on glioblastomas (salaried post-doctoral associate) in the context of his doctoral dissertation, University of Illinois, Peoria, USA
- 10/2010-04/2011: Educational leave to attend training, General Neurology Department and the Department of Epilepsy, Geneva University Hospital, Switzerland (laboratory research on cerebrovascular accidents)
- 05/2012-10/2012: Clinical research, Laboratory of Epilepsy and Brain Mapping, Neurology Clinic, Geneva University Hospital, Switzerland
- 10/2013-04/2014: Specialty training, Department of Neurosonology, Neurology Clinic, Geneva University Hospital, Switzerland (salaried position)
- 07/2013-10/2013: Postgraduate training, Department of Neurosonology, Neurology Clinic, Geneva University Hospital, Switzerland (salaried position)
- 10/2012-07/2013: Postgraduate training, Department of Vascular Brain Diseases, Neurology Clinic, Geneva University Hospital, Switzerland (salaried position)
Academic Titles
- Registrar, Cerebrovascular Accident High Dependency Unit, Metropolitan Hospital, Athens
- Neurology Associate, Olympion Private Clinic, Patra
- PhD, University of Ioannina Medical School, Doctoral thesis summa cum laude, thesis topic: Pervasiveness and Angiogenesis in Gliomas
- Fellow of the European Board of Neurology
- Postgraduate training in vascular brain diseases, electroencephalography and neurosonology, Geneva University Hospital
- Postgraduate training in key research on brain tumors, University of Illinois, USA
- Domestic (Ministry of Health) and international (ESNCH) certification in Neurosonology
- Member of the European Society of Neurosonology and Cerebral Hemodynamics
Educational Workshops / Seminars
- March 2015: 26th Continuing Education Seminar, training in CNS Vasculitis, Hellenic Neurological Society, Athens
- 16th Congress of the European Federation of Neurological Societies, Stockholm, Sweden
Training courses:
- Diagnosis and treatment of Epilepsy
- Clinical assessment of the vestibular system
- Clinical Neurophysiology - Nerve Conduction in the upper limbs
- June 2012: Training seminar in cerebrovascular accidents, Hellenic Neurological Society, Alexandroupoli
- May 2012: Epilepsy Surgery Seminar, Hellenic Neurological Society, Thessaloniki
- February 2010: Training seminar on movement disorders, Hellenic Neurological Society, Athens
Educational Work
- 10/2014-10/2015: Monthly classes/presentations to students at the Faculty of Medicine, within the context of their clinical practice training in Neurology; course: "Myasthenic Syndromes and Muscular Dystrophies".
- 10/2012-10/2013: Neurology Clinic, University Hospital of Geneva. During his postgraduate training he contributed to the clinical practice training of 5th year students of the Faculty of Medicine at the University of Geneva.
- 07/2007-04/2011: Neurology Clinic, University Hospital of Patra. During his 4-year specialty training he contributed to the clinical practice training of 5th year students of the Faculty of Medicine at the University of Patra. Monthly classes/presentations to students of the Faculty of Medicine within the context of their clinical practice training in Neurology; courses: "Kinetic Mechanism”, "Cranial Nerves", "Cortical Functions”.
- 09/2009 -07/2010: Hourly paid instructor, Physiotherapy TEI of Patras, Aigio, Musculoskeletal System Anatomy Lab.
SCIENTIFIC ACTIVITIES
Scientific Journals
- Mechanisms of angiogenesis in gliomas. Kargiotis O, Rao JS, Kyritsis AP. J Neurooncol. 2006;78(3):281-93.
- Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model. Tsung AJ, Kargiotis O, Chetty C, Lakka SS, Gujrati M, Spomar DG, Dinh DH, Rao JS. Int J Oncol. 2008;32(3):557-64
- Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma. Kargiotis O, Chetty C, Gondi CS, Tsung AJ, Dinh DH, Gujrati M, Lakka SS, Kyritsis AP, Rao JS. Oncogene. 2008;27(35):4830-40.
- uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo. Kargiotis O, Chetty C, Gogineni V, Gondi CS, Pulukuri SM, Kyritsis AP, Gujrati M, Klopfenstein JD, Dinh DH, Rao JS.Int J Oncol. 2008;33(5):937-47
- RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells. Gogineni VR, Kargiotis O, Klopfenstein JD, Gujrati M, Dinh DH, Rao JS. Int J Oncol. 2009;34(1):209-18
- SPECT neuroimaging and neuropsychological functions in different stages of Parkinson’s disease. Paschali A, Messinis L, Kargiotis O, Lakiotis V, Kefalopoulou Z, Constantoyannis C, Papathanasopoulos P, Vassilakos P. Eur J Nucl Med Mol Imaging. 2010;37(6):1128-40.
- Quality of life in multiple sclerosis: effects of current treatment options. Kargiotis O, Paschali A, Messinis L, Papathanasopoulos P. Int Rev Psychiatry. 2010;22(1):67-82.
- Effects of irradiation on tumor cell survival, invasion and angiogenesis. Kargiotis O, Geka A, Rao JS, Kyritsis AP. J Neurooncol. 2010;100(3):323-38.
- Masseter muscle function after percutaneous balloon compression of trigeminal ganglion for the treatment of trigeminal neuralgia: A neurophysiological follow-up study. Chroni E, Constantoyannis C, Prasoulis I, Kargiotis O, Kagadis GC, Georgiopoulos M, Polychronopoulos P. Clin Neurophysiol. 2011;122(2):410-3.
- Bilateral blepharospasm as the presenting symptom of Sjögren’s syndrome with evidence of central nervous system involvement. Odysseas Kargiotis, Panagiotis Papathanasopoulos, Terzis Efstathios, Georgios Yiannopoulos and Andrew P. Andonopoulos. Acta Neuropsychiatrica, Volume 22, Issue 5, pages 263–265, 2010
- Epilepsy in the cancer patient. Kargiotis O, Markoula S, Kyritsis AP. Cancer Chemother Pharmacol. 2011;67(3):489-501
- Diplopia due to systemic lupus erythematosus in a child: a rare clinical presenting sign of the disease. Georgakopoulos CD, Kargiotis O, Eliopoulou MI, Makri OE, Exarchou AM, Papathanasopoulos P. J Child Neurol. 2011;26(12):1576-9.
- Association of TNF-857C>T, TNFRSF1A36A>G, and TNFRSF1B676T>G Polymorphisms with Ischemic Stroke in a Greek Population. Markoula S, Chatzikyriakidou A, Giannopoulos S, Odysseas K, Markou S, Vemmos K, Georgiou I, Kyritsis AP. Stroke Res Treat. 2011; 2011:920584.
- Recombinant tissue plasminogen activator induces blood-brain barrier breakdown by a matrix metalloproteinase-9-independent pathway after transient focal cerebral ischemia in mouse. Copin JC, Bengualid DJ, Da Silva RF, Kargiotis O, Schaller K, Gasche Y. Eur J Neurosci. 2011;34(7):1085-92.
- Associations of ESR2 AluI (G/A) polymorphism with ischemic stroke in Caucasians. Markoula S, Milionis H, Lazaros L, Spengos K, Vassilopoulou S, Chatzistefanidis D, Kargiotis O, Georgiou I, Kyritsis AP. J Neurol Sci. 2012;316(1-2):126-30
- Localization of the epileptogenic tuber with electric source imaging in patients with tuberous sclerosis. Kargiotis O, Lascano AM, Garibotto V, Spinelli L, Genetti M, Wissmeyer M, Korff CM, Momjian S, Michel CM, Seeck M, Vulliemoz S. Epilepsy Res. 2014;108(2):267-79.
- Investigation of coronary-subclavian steal syndrome using color duplex ultrasounds: literature review and clinical presentation of studies. Odysseas Kargiotis, Fabienne Perren. Neurology Journal, Vol 23, issue 1
- An unusual case of isoniazid toxicity. Kargiotis O, Marangos M., Polychronopoulos O. Neurol Sci. 2015 Feb 11
Books Chapters
- Odysseas Kargiotis and Athanasios P. Kyritsis. Radiation-induced peripheral nerve disorders. In WenPY, Schiff D, Lee EQ (eds). Neurologic complications of cancer therapy, chapter22, Demos Medical Publishing, 2012, pp 355-371
Referee
- British Journal of Cancer
- Journal of Neurosciences in Rural Practice
- Current Medical Literature - Multiple Sclerosis
- Drug Delivery Letters
- Journal of Neuroimaging
- Neuroimmunology and Neuroinflammation
Monographs
- Doctoral thesis (PhD), University of Ioannina, Medical School: “Pervasiveness and Angiogenesis in Gliomas"(2009)
Active Participation in Conferences
- November 2015: 3rd Panhellenic Conference on Health Management Crisis, Athens
Lecturer on "Neurological disorders that require special treatment in the health sector”; lecture topic: “Cerebralvascular Accident” - June 2015: 27th National Neurology Conference of the Hellenic Neurological Society, Alexandroupoli
Lecturer; topic: "Intracranial ultrasonography" - June 2015: 10th Meeting of the Hellenic Haemapheresis Society, Athens
Lecturer; topic: "Neurological events in thrombotic micro-vascular disease" - May 2015: 48th Panhellenic Ophthalmology Congress, Olympia
Oral abstract presentation, session: "Retinal Pathology & Uva”, title: "Selective Intra-arterial Ophthalmic Artery Thrombolysis during a Central Retinal Artery Occlusion", Kargiotis O., Magkoufis G., Gkeka A., Maleviti N., Safouris A., Stamboulis E. - May 2015: 2nd Geriatrics Congress on Primary Health Care, Kyllini Beach Resort
Lecturer; topic: “Neurodegenerative diseases in old age” - March 2015: 26th Continuing Education Seminar, training in CNS Vasculitis, Hellenic Neurological Society, Athens
Lecturer; topic: “CNS Vasculitis: characteristics, symptomatology, main differential diagnosis” - March 2015: Spring Meeting of the Opthalmological Society of Western Greece and the Peloponnese, Ioannina
Open topic announcement; title: "The usefulness of duplex ultrasounds in the diagnosis of temporal arteritis" - December 2014: Hellenic Association of Gerontology and Geriatrics Winter School, Vityna, Arcadia
Lecturer; topic: "Newer approaches for cerebrovascular accidents”
Colloquium Chairman, colloquium themed: "Neurosurgical problems in old age” - November 2014: Scientific Event, themed “Lysosomal Storage Diseases Niemann-Pick disease type C and Gaucher disease type 1” , under the auspices of the Department of Hematology, General Hospital of Patra and in collaboration with the Children’s Clinic and Neurology Clinic of the General Hospital of Patra, University of Patra
Lecture topic: “Think again. Think Niemann Pick-C” - May 2014: 19th European Society of Neurosonology and Cerebral Hemodynamics (ESNCH) meeting, Rome, Italy
Oral paper presentation “Etiological diagnosis of intracranial arterial stenosis: comparison of TCCD with 3T MRI (3D-VISTA) imaging”. F. Perren, O. Kargiotis, IM. Vargas. HUG, Dept. Neurology, Neurosonology Unit, Dept. of Radiology, Neuroradiology Unit, 1211 Geneva, Switzerland - June 2013: 2nd SFCNS Congress, Swiss Federation of Clinical Neuro-Societies, Montreux, Switzerland
Abstract presentation in the poster session. “Localization of the epileptogenic tuber with electric source imaging in patients with tuberous sclerosis”. O. Kargiotis, A.M.. Lascano, V. Garibotto, L. Spinelli, M. Genetti, M. Wissmeier, C.M. Michel, M. Seeck, S. Vulliemoz; Department of Neurology and Nuclear Medicine, University Hospital of Geneva, Switzerland - May 2012: ARVO Annual Meeting in Fort Lauderdale, Florida
Abstract presentation in the poster session. “Analysis of Gene Expression in Acute Ischemic Neuroretinas: A Genome-wide Screen Discriminating Occlusion (BRVO) Versus Laser Effects in Rats”. Aliki Geka, Cassandra Oropesa Ceballos, Angeliki Andrianaki, Odysseas Kargiotis, Olivier Schaad, Alain Conti, Constantin J. Pournaras. Ophthalmology, Geneva University Hospital, Geneva, Switzerland; Faculty of Medicine, University of Geneva, Geneva, Switzerland - May 2010: 24th Panhellenic Congress on Neurology, Kos
Free paper. “SPECT neuroimaging and neuropsychological functions in different stages of Parkinson’s disease”. Paschali A, Messinis L, Kargiotis O, Lakiotis V, Kefalopoulou Z, Constantoyannis C, Papathanasopoulos P, Vassilakos P. Departments of Nuclear Medicine and Neurology, University of Patras, Greece - April 2008: Annual Meeting of the American Association for Cancer Research, San Diego, CA, USA
Abstract presentation in the poster session and publication in the 2008 Proceedings of the American Association for Cancer Research. “uPA/uPAR downregulation by siRNA inhibits radiation-induced migration, invasion and angiogenesis in vitro and decreases tumor growth in vivo”. Odysseas Kargiotis, Chandramu Chetty, Venkateswara Gogineni, Christopher Gondi, Sai Murali Pulukuri, Athanasios Kyritsis, Meena Gujrati, Dzung Dinh and Jasti Rao University of Illinois, College of Medicine at Peoria, Peoria, IL, USA University of Ioannina Medical School, Ioannina, Greece - April 2008: Annual Meeting of the American Association for Cancer Research, San Diego, CA, USA
Abstract presentation in the poster session and publication in the 2008 Proceedings of the American Association for Cancer Research. “RNA interference-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK in IOMM-Lee cells.” Venkateswara Rao Gogineni, Odysseas Kargiotis, Meena Gujrati, Dzung Dinh and Jasti Rao. University of Illinois, College of Medicine at Peoria, Peoria, IL, USA - May 2007: Annual Resident Research Day of St Francis and Methodist Hospitals of Peoria, Peoria, IL, USA
Abstract: “Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model.” Tsung AJ, Kargiotis O, Chetty C, Lakka SS, Gujrati M, Spomar DG, Dinh DH, Rao JS. University of Illinois, College of Medicine at Peoria, Peoria, IL, USA - April 2007: Annual Meeting of the American Association for Cancer Research, Los Angeles, CA, USA
Abstract presentation in the poster session and publication in the 2007 Proceedings of the American Association for Cancer Research “Adenovirus-mediated transfer of siRNAs against MMP-2 mRNA results in impaired growth, invasion and migration of glioblastoma cells as well as inhibition of tumor-induced angiogenesis.” Odysseas Kargiotis, ChandramuChetty, Christopher Gondi, Sajani Lakka, Dzung Dinh, Meena Gujrati and Jasti Rao. University of Illinois College of Medicine at Peoria, Peoria, IL, USA
